ClinTrial

It's really typical to see people with high cholesterol amounts due to the modern lifestyle and fat food we eat. Most of the time higher cholesterol levels might be lowered by a rigid eating habits and cardio exercises such as walking. When the fat levels are far too high and they need to be lowered quick doctors opt drugs such as Statins. It may be the most-recommended and successful medicine against excessive amounts of cholesterol. Statins consists of a chemical that reduces cholesterol generation by the body and also reduces absorption of fat from the food we consume, which in return lowers blood fat amounts and restricts cholesterol accumulate in the arterial blood vessels. Differences in sort...

The word cholesterol has become synonymous with poor health. Indeed, one does not typically hear the word used, or see it printed, unless it points to yet another distressing fact -- that high cholesterol is the number one factor for coronary heart disease, and the number one cause of heart attacks[i]. However, cholesterol is, in itself, not a negative thing. On the contrary, cholesterol plays a vital role in forming cell membranes, regulating hormones, insulating nerves, and more. The problem with cholesterol therefore lays not in cholesterol itself, but the amount of cholesterol present in the bloodstream. For most Americans who talk and read about this subject, the scenario almost always...

diagnosed with mesothelioma, there are different treatment options that you can choose, which are largely based on how advanced the disease is and where it is located in the body. Some people with mesothelioma may be eligible and may wish to participate in clinical trials for the treatment of the disease. Before one decides to participate in a clinical trial, it is wise to discover what is involved in the trial and whether or not your doctor and family feels that it is a viable option. Some of the things that you should ask your doctor are: • Which treatments are used in the trial? • What are the differences in this treatment and conventional treatments? • What side effects can be...

If you've ever wondered how companies know whether a new drug really works or where scientists find out whether coffee is truly good or bad for your health, paid medical studies are the answer. And individuals can make a decent amount of pocket change working for these scientists as a human "guinea pig." As anyone who's had to pay the pharmacist knows, medicine is big business. In order to make sure their claims are accurate, companies pay volunteers to donate their time and bodies as the "normal" control group when they test new medicines and treatments. Some of these clinical trials are complex long-term projects requiring hundreds of volunteers who visit the clinic for weekly blood draws or take...

Vitamin A is vital for a variety of bodily functions. These include: - Maintaining healthy teeth. - Building strong bones. - Strengthening the optical system. - Growth and maintenance of healthy skin and tissue. - Protection from cardiovascular disease and cancer. - Promoting good vision, particularly in low light. - Reproduction and breastfeeding. - Cell division and cell differentiation (a process in which a cell becomes part of the brain, muscle, lungs, blood, etc.). - Regulation of the immune system. Vitamin A occurs in 2 forms: preformed Vitamin A, also known as active Vitamin A, and proVitamin A. Preformed Vitamin A is better known as retinol. This is considered the active form because it...

From stem cells to plastic and reconstructive surgery programs, Mexico is becoming an increasingly accessible, affordable and popular destination for medical tourists not only from neighboring North America, but other Latin countries and international travelers. Because stem cell technologies are still under study and currently undergoing Phase I and Phase II clinical trials in the United States and treatments and therapies have not been approved for release, individuals hoping for alternative treatments for spinal injuries, neurodegenerative disorders, and paralysis caused by a trauma are seeking help south of the border. Clinical Trials Slow Clinical trials and studies researching the efficacy of...

Completed by volunteers, FDA (short for Federal Drug Administration) clinical trials are a series of tests, experiments, and surveys that are done to collect safety information regarding drugs and other materials. In a long and lengthy process, these are performed only after an extensive number of tests have been done and enough information has been completed and deemed as being satisfactory. From there, the Health Authority and Ethics Committee give their stamp of approval to the country whom is running the trials. However, before getting to the final step, a lot of work has to be done. Due to the fact that FDA clinical trials are so expensive, in the beginning, only a small portion of volunteers...

Historically pharmaceutical companies did all their own research and development in house. Over the last few years however, while the cost of discovering and developing a new drug has rocketed to almost $1 billion the number of new drugs approved has dropped considerably, to almost half of the level in the nineties. Many blockbuster pharmaceuticals are coming off patent in the near future. In addition, newer technologies are resulting in the growth of the number of candidate drugs that need to be tested. These pressures are combining to change the historical models operated by pharmaceutical companies. One of the changes is that pharmaceutical companies are increasingly turning to specialist...

ng wouldn’t have been a serious problem if it wouldn’t have affected one’s personality. Balding makes people look aged and at times meek. The hair’s so deeply integral to one’s personality that loosing it affects people moral and mental status. It is especially difficult to adjust when the hair falls out quickly. We can only hope for acceptance sooner or later. But this roller coaster ride may make us feel awkward, embarrassed and at times even angry. Gaining acceptance is a gradual process. But you should also accept the fact that using proper medications like Propecia can support your personality to a great extent. It is a medicine taken in tablet form. FDA trials...

Having beautiful, smooth and firm skin allows one to feel good about their appearance and have a healthy self-image - qualities that help people live better, longer. To this end, biochemist Dr Chantal Burnison designed the breakthrough ingredient Ethocyn, used in the finest wrinkle creams today. As confirmed by eminent M.D. and skin physiologist Dr. Peter T. Pugliese, "The single most important cause of age related skin wrinkles and sagging is the loss of skin elastin fibers. Everyone, whether female or male, will begin to lose skin elastin fibers at age 25. Elastin fibers are the restorative force in the skin." Elastin gives the skin resiliency and the ability to stretch and snap back into shape...

rchers have known for a long time that the sea holds many great cures and treatments for humans. Some of the compounds made naturally in sea life are not found anywhere on land and have proven to help humans in a number of ways. Now researchers are saying that fish oil that contains omega-3 fatty acids can help people fight depression. Doctors at the Massachusetts General Hospital who have watched the clinical trials report that they are impressed with the results. These early results should encourage more testing. Since fish oil does not have negative effects, it is a study that can easily be conducted on a wide scale. Many scientists and researchers first became interested in fish oil when they...

A Clinic in Honduras, has been quietly and successfully using an Oleander extract to treat patients previously diagnosed with terminal cancer since 2001. Many patients from the U.S. have made the pilgrimage and returned home free of cancer. Patients told by their doctors that there was nothing more to be done, have gone to Honduras and returned home either completely cured or in dramatic remission. And all this due to the properties of the simple oleander plant. So what is the secret? Well, there isn't any. The USFDA knows all about it, but in deference to our own massive pharmaceutical and cancer industries, they maintain the position that the oleander extract used by this Clinic is "an unproven...

If you think drug research is honest, you need to read this. We would like to think that the research done by the pharmaceutical companies is honest, but more than one news story has shown otherwise. If we had the political will, or if the FDA was less political, drug trials could be made more honest almost immediately with one simple procedure. Unfortunately, that change has been fought by the drug companies. Let's see why. The English newspaper, The Guardian, recently reported on several systematic reviews of drug research. They clearly showed that pharmaceutical industry studies and clinical trials report positive results far more often than those funded independently (funded by those not selling...

Nowadays, renting is often more cost-effective than purchasing and this holds true even for CPAP machines. If you have mild to moderate sleep apnea and you appear to respond to medications, lifestyle changes and adjunct therapy for your health condition, then renting is the best option for many reasons. Benefits For one thing, you need not spend hundreds of dollars purchasing a machine that you will be using on a temporary basis. You are better off spending the purchase cost on something else, say, overdue bills. For another thing, you will not be saddled with the maintenance costs of the CPAP machine. Indeed, even as you strive to be healthy, your pockets will also suffer a dent. Plus, you also...

Brain training programs include those exercising regimes that involve various puzzles and activities that are fabricated into different computerized programs, flash cards, video gaming devices, PDA's and even in book formats. The basic aim of brain games is to stimulate thinking capabilities and sort out several mental problems. In the recent studies conducted in neurology, medical professionals have discovered that daily brain improvement activities have shown remarkable results even with patients with brain impairments. According to several researchers daily brain training exercises really help in improving blood flow to brain, enhancing overall brain functions, and possibly slowing the ageing...

> Stem Cell Research is big business in the North East. It boasts some of the finest research facilities in the country, if not Europe coupled with clinical expertise it creates the perfect spot to develop your stem cell research organisation. Organisations are always looking for opportunities to expand; we offer some key tips on the best places to look. Companies are often looking for opportunities to develop their business further. In the stem cell research area it is important that you have the right staff and the right backing in the region you are moving into. North East England has one of the highest concentrations of stem cells researchers in the UK.  The resources all ready located in the...

In this world with the big amount of increase in pollution and harmful exposures coming at us from almost all angels in our daily lives, damaging our body inside and on the outside ruining or skin, we can use all the extra help we can get. What are free radicals? Why are they damaging to the human body? And how doe's vitamins and the other antioxidant nutrients help protect the body against free radicals? Cells are composed of many different types of molecules. Molecules consist of one or more atoms of one or more elements joined by chemical bonds. Electrons are involved in chemicals reactions and are the substance that bonds atoms together to form molecules. Helping with fighting these harmful...

Finding the best omega3 pills can be easy, or it can be hard. It all depends on what information you read. There's a lot of misinformation out there on what exactly makes high-quality omega3 pills. You see, many manufacturers and companies take shortcuts to make more money. For example, manufacturers might use inferior fish, and they might even use the whole fish in the process of producing the fish oils. Why is the whole fish bad to include? When you use the whole fish, you use the liver of the fish, which is filled with toxins and heavy metals. The liver is used to purify and clean the blood of both humans and animals. Only the best parts of the fish should be used to produce fish oil dietary...

Mesothelioma is a fairly new type of cancer that is very serious and life threatening, as with most types of cancer. One thing that makes mesothelioma such a serious condition is that it is usually not found until the late stages of the cancer, causing the survival rate to be low. This is because the symptoms don't usually arise until the late stages. By this time the patient most likely doesn't have much longer to live. Studies show most patients who are diagnosed with mesothelioma have a year or less left to live. Along with diagnosis being difficult and delayed, mesothelioma is also fairly uncommon and we are still learning more about the disease. However, some studies show that one out of every...

Arthritis is a name derived from the Greek language and describes the disease well. "Arthron" means 'joint' and "itis" means 'inflammation'. This is therefore a disease of the joints in the body. Arthritis has been found on skeletons dating back to prehistoric times and presently doctors estimate that over a hundred million people suffer from some form of the disease all over the world. Characteristics or symptoms of arthritis include inflammation and pain at the joints such as the elbows, hips, knees, ankles, wrist or just about every joint in the body. Believe it or not, but arthritis can also affect the skin, eyes and chest too besides the musculoskeletal system. There may be a reddening of the...

Drugs sold as a cheaper alternative to brand named products are called generic drugs. Usually, generic drug companies cannot patent their active ingredients, but they can patent their own unique formulation. The Food and Drug Administration of the United States of America governs all medications and according to them the generic drug is identical to the brand named drug, legally. Therefore, the same laws apply to these drugs as their branded counterparts where strength, administration and safety are concerned. They must contain the same active ingredient as the branded product and be within acceptable bioequivalent ranges. Once the patent expires on a branded drug, generic drugs can be introduced...

Vitamin A is the first vitamin discovered. This is a fat-soluble vitamin. Some of the benefits of Vitamin A: - It helps maintain our vision; it especially affects our ability to see in the dark. Vitamin A has metabolites that help our eyes to adjust themselves from bright light to dim light or darkness. - It helps the body to maintain healthy skin, hair, teeth and bones. - It is necessary for the proper functioning of the reproductive system. - It promotes a healthy immune system. - It is considered as an essential nutrient for the overall growth and development of the body. - It is known to have antioxidant properties that help to counterbalance free radicals in the body. Free radicals can cause...

Collagen is the necessary protein your skin needs to keep it firm and young looking but your body's natural collagen production decreases as you grow older. To prevent wrinkles and sagging skin you need to find an anti aging cream that is pro collagen to increase your own natural collagen production. Many anti aging skin care products contain collagen fillers but because the collagen molecules are too large to penetrate deeply into your skin's layers these only sit on the surface and give the appearance of a smooth, radiant complexion. This is only an illusion and it will disappear the next time you wash your skin. If a collagen cream doesn't work then how can a pro collagen cream be any better? A...

Did you know that what you put on your skin is not nearly as important as what you put on your plate? To have truly fabulous skin that is vibrant, glowing and younger looking you need to nourish your skin from within. The more attention you pay to what you eat and drink, the more youthful and vibrant you skin will be. You see, the skin require certain nutrients to stay silky smooth and healthy. Starve your skin enough and over time, it's going to show. If your diet is missing certain nutrients, skin problems can result, some of them serious. Some skin experts agree that dietary factors can influence the look and condition of your skin. Elaine Linker, PhD, biochemist and co-founder of DDF Skin Care...

Do you suffer from migraines? Consider going natural as you try to manage your migraine headaches. One very interesting alternative treatment migraine headache sufferers should consider is called Feverfew. An easily found flowering plant, Feverfew can be an effective part of an overall migraine preventative program that is not heavily dependent upon medications and is free of the many side effects that can go with migraine headache medications. Tanacetum parthenium is the unpronouncable scientific name for what we call Feverfew. The Feverfew plant looks much like a daisy with its white flowering petals and yellow centers. Nice looking flower but it is the small yellowish green leaves on the stem...

> Garlic health benefits and medicinal properties have long been known. Garlic has long been considered a herbal "wonder drug", with a reputation in folklore for preventing everything from the common cold and flu to the Plague.  There are two main medical ingredients which produce the garlic health benefits: allicin and diallyl sulphides. 1. Garlic makes a wonderful health supplement but the garlic cure is no substitute for the basics: sensible eating and appropriate exercise. Garlic should be seen as part of a healthy lifestyle - not as an alternative to it. Always consult your doctor first regarding any medical condition. 2. Scientists have also looked at the role garlic plays in helping prevent...

Is Carlson fish oil really worth your money? It is one of the top brands that deliver good omega-3 supplements to thousands of people all over the world. But you still have to ask yourself if there is a better deal out there. Carlson fish oil is primarily made up cod and salmon. These are excellent sources of omega-3's, but recent clinical trials have shown that when tuna and hoki oil are blended together, they can have up to 2 1/2 times the health benefits when compared to normal omega-3 supplements, such as Carlson fish oil. I'm not saying that Carlsons fish oil is bad, not at all, it is a very good product. But if you're anything like me, you want to find the best deal out there that can give you...

Not only is the skin around the eyes sensitive, it is also extremely vulnerable to signs of aging. This is where fine lines, sagging skin, puffiness and other signs of wear show up frequently. Because of this, the areas around the eye often need some special care. In particular, an effective under eye firming serum can assist in revealing younger looking skin and resolve the issues that can make us look older. Not only is the area around the eyes thinner, it is very susceptible to environmental damage. Things like air pollutants and UV radiation can easily damage the skin. Because of this, it is essential that any products you use do not contain any harmful chemicals that may cause problems, or be...

Millions of people are using cod fish oil and other omega-3 supplements. Research and studies have shown that essential omega-3 fats can help your body reduce cholesterol, support your heart, improve your immune system, reduce arthritis symptoms, increase energy and increase happiness. To get all these benefits, is cod fish oil really the best option? Cod fish oil contains a lot of vitamin D, which helps keep your bones strong. Scientists also warn that it may be easy to overdose on cod fish oil, which is why natural health experts now recommend that you choose an omega-3 supplement that does not have this risk. For example, recent clinical trials have found that a blend of hoki and tuna oil is up...

Every man can remember the day they first noticed their receding hairline, for some it's swiftly followed by a bald spot. This is a condition that they have little control over. As yet, there is nothing available to stop the balding process, yet there have been some quite exciting developments in treatments over the past couple of decades. With further advancements, who knows? There are some treatments on the market which pledge to fight continuing hair loss. Depending on how far your baldness extends and how much you can afford to spend on treatment every much determines which ones would be worth trying. One of the most popular compounds used to counter act hair loss is Minoxidil; this is found in...

I don't know a thing about you but I'll bet (just like myself at some point) one of your searches involves seeking out the best anti aging skin care guide and treatment that will instantly erase those unwanted telltale signs of aging. Like so many others approaching their forties and/or fifties, either you're beginning to bear witness to those first signs of aging or perhaps you're witnessing every now and then, the constant formation of new wrinkles, bags, and dark circles that apparently don't heed to the command of: "shoo away, go away now!" I am here to say that it is never too early or too late to begin an anti-aging skin care treatment. Aging can take a toll on both our inner and outer self...

Clinton's recent quadruple bypass surgery has been largely debated. Being on the South Beach Diet made everybody wonder how the former president's illness advanced so much as to need to be surgically corrected. Some even blame it on the diet. Some wonder why the diet didn't help avoiding surgery. Fact is that, first of all, being on the South Beach Diet for a relatively short time or being on any other diet couldn't work miracles and suddenly reverse atherosclerosis. It is true that recent clinical trials have indicated that with a reduced cholesterol level, reduced weight and regular exercise heart disease may regress but a longer period of time is required to restore what was built in decades...

The ever-increasing interest in the weight-loss product Hoodia gordonii as a truly helpful dietary supplement, has been sweeping the markets like a brush fire. At present, many dietary supplement manufacturers are producing different brands of products that supposedly contain the actual plant from South Africa. These products carry variable claims of biological activity. While the realm of Internet advertising has become frenetic these days, and some may be deceptive in some aspects, and positively corrupt in others. It's a fact that a lot of Internet advertisements insert false claims or misleading information about the product or the natural ingredient, and its "form" in dietary supplements...

We know that CoQ10 can actively help to increase the amount of blood flow you have as well as cells pumping back and forth through your heart's chambers. When it comes to a discovery such as this one, science and technology has dug deeper in order to find new CoQ10 research results and the results have been absolutely amazing. Here are a few new diseases that are currently being researched in order to improve human life. There have been recent clinical trials conducted that have shown that patients who have signs of the early stages of Parkinson's disease can utilize CoQ10 in order slow down the disease and hopefully stop it altogether. This of course is brand new CoQ10 research that is being...

What does Omega -3 fish oil do for you. Omega-3 is the name given to a family of polyunsaturated fatty acids. The parent Omega-3 - alpha-linolenic acid (ALA) - is described as 'essential'as, like vitamins, it must be obtained from diet. Omega-3 fatty acids havebeen well documented for their ability to reduce inflammation, with stronganti-inflammation properties. Adding fats to your diet is essential if youwant to live a healthy lifestyle that results in feeling and looking great,but it has to be the right kind of fats. Essential fatty acids fall withinthis category and are a crucially important addition to anyone's diet. Omega-3essential fatty acids are made up of two components: DHA (which stands...

The last year hasn't been a good one for vitamin E. Once considered a wonder supplement, an inexpensive and harmless pill that might prevent heart disease, cancer and Alzheimer's, a flurry of recent clinical trials suggest it does none of those things. Some even suggest there is a small chance it could be harmful in higher doses. Yet while the oily little capsule apparently can't keep people alive longer, it refuses to die, in part because in nearly every one of the recent negative studies some caveat or contradictory finding creates a glimmer of hope. It also doesn't hurt that the dietary supplement industry continues to promote vitamin E and offers experts to refute some of new research. "It doesn...

A recent article published in The Daily Mail has explained just how eating tomatoes along with other fruits and other food stuffs high in vitamin C can help towards the reduction of prostate and other cancers. One of the main active components in the tomato is lycopene, this is what gives the tomato its red colour. Lycopene is easily absorbed into the bloodstream along with vitamin C and In recent clinical trials, it was found that people diagnosed with prostate cancer who regularly eat tomatoes and other products high in Vitamin C and lycopene in their regular diet were found to have a 44% reduction in the chance of the disease spreading. Naturally we can all eat as many tomatoes and as much fruit...

Prenatal omega 3 supplementation is crucial for the development of your baby. Studies have shown that mothers that supplement with omega-3 fatty acids before, during, and after their birth have a much easier time in their pregnancy and have a higher chance of giving birth to a smarter child. Prenatal omega 3 supplementation has been shown to help with the development of your baby's brain, eyes, heart, and increase the mothers' wellness and decrease the odds of premature birth. Finding the best product is something that is very important if you're looking to supplement with omega-3's. This is because there are a lot of low-quality products out there that might contain heavy metals and other poisons...

Are Antioxidants? Antioxidants are molecules which can safely interact with free radicals and terminate the chain reaction before vital molecules are damaged. Although there are several enzyme systems within the body that scavenge free radicals, the principle micronutrient antioxidants are vitamin E, beta-carotene, and vitamin C. Selenium, a trace metal that is required for proper function of one of the body's antioxidant enzyme systems, is sometimes included in this category. The body cannot manufacture these micronutrients so they must be supplied in the diet. Why Eat Fish Weekly? Best choices are oily fish rich in healthy omega-3 fatty acids, such as herring, sardines, salmon, lake trout...

Let us face it; 30% of population in the West, suffers from signs and symptoms of inflammation. The reason of this exorbitant figure is the eating habits and the life style we follow these days. Lack of exercise and poor diet is the root cause of appearance of signs and symptoms of inflammation in the body. The processed, oily and junk food like coke, chips, red meat, cheese, etc. we eat contains omega6 fatty acids, which have inflammatory properties and very less amount of omega3 fats, which have anti-inflammatory properties. This imbalance of 6-type fats and 3-type fats results in uncontrolled inflammation in the body. Experts recommend that the ideal ratio of omega6 to omega3 fats is 4:1. However...

Just what are antioxidants and can they do anything to help prevent or fight cancer? Information from the National Cancer Institute describe antioxidants as substances that may protect cells from the damage caused by unstable molecules known as free radicals. Free radicals may lead to cancer. Antioxidants interact with and stabilize free radicals and may prevent some of the damage free radicals otherwise might cause. Examples of antioxidants include beta-carotene, lycopene, vitamins C, E, and A, and other substances. Can antioxidants prevent cancer? Considerable laboratory evidence indicates that antioxidants may slow or even prevent the development of cancer. However, information from recent...

It has been established that foods high in soluble fiber promote good health particularly because this fiber binds to fatty acids and allow for the slow absorption of sugar. Health experts have also linked the intake of fiber to decreased risk of suffering from diseases such as constipation, diarrhea, heart-related illnesses and even cancer. What is It? Considered to be a fraction of the dietary fiber, soluble fiber is actually composed of polysaccharides not derived from starch and plant components like lignin, waxes, oligosaccharides and pectins. Unlike insoluble fibers, it changes during passage along the digestive tract mainly due to the action of fermenting bacteria. Benefits Because it readily...

When looking for an effective natural treatment for psoriasis, look no further than the Oregon grape. You may not have heard of this extraordinary herb that is now being touted as a safe and extremely successful treatment for mild to moderate psoriasis. What exactly is the Oregon grape and why all the hype? The Oregon Grape (mahonia aquifolium) is not really a grape, but an evergreen shrub that gets clusters of purple berries, the color and appearance of which look a little like grapes. The berries are edible, although quite bitter in taste and usually have to be sweetened to make them palatable. The leaves of the plant look like holly and the flowers, which appear in late spring, are a beautiful...

It has become common knowledge that omega 3 supplements are a needed part of our daily diets. It can be extremely confusing when trying to buy the best fish oil capsules. There are so many varieties and brands on the market today, how do you know which one is the best or the safest? There are a few things you can do to make sure you are buying the best fish oil capsules available today. These secrets are easy and quick to follow. 1. Read the label: you want to see both DHA and EPA as this combination has been proven to lower cholesterol and reduce the risk of heart disease as well as reducing depression. 2. Check the dosage: it should give you 1,000 mg of DHA and EPA in order to be effective. 3...

Although we are beginning, largely as a result of education, to detect more cases of prostate cancer in their early stages, unfortunately all too many cases are still not being detected until they are quite advanced. Advanced prostate cancer refers to a cancer which has spread outside of the prostate gland itself and is divided into stage 3 cancer, in which the disease has spread into the pelvic tissue surrounding the prostate gland, and stage 4 cancer, in which the disease has spread, or metastasized, into other areas of the body, typically being carried by the lymphatic system. Although not easy, stage 3 prostate cancer can often be treated quite effectively and it is possible to cure prostate...

Easy, they reduce puffiness, crows feet and dark circles under your eyes. At least that's what the ads say. And they do moisturize which will help reduce wrinkles. But many of the top names spend more on their advertising than they do on their ingredients. It's true, do you know some of those spokes models are paid more than 10 million dollars to smile for the camera? It makes me crazy at the money spent pushing products that are often nearly identical to one another. So you know what I did? I started researching skin care and decided I was going to find real value in my eye cream. A product that not only moisturized and plumped up those fine lines under my eyes but also really helped fade those...

Do Stop Smoking Shots sound like a miracle cure? Have you ever said, "If they could only come up with a shot that could make me quit, then I could finally do it." The fact is, there are no miracle cures for Nicotine addiction, but there are some methods that have shown great promise to finally help smokers kick the addiction. First of all, if anyone ever advertises a 100% success rate, that's your first clue to put your money back in your pocket. Secondly, if a program doesn't specialize in treating Nicotine addiction, then they probably don't know a lot about helping you succeed. Sure, doctors know that smoking is bad for you and they know how to write a prescription, but quitting smoking is more...

Part 3: This Porridge is too Cold. In Part 1 of this post, we dumped on clinical trial translation in general, and in Part 2 we dumped on the gold standard of clinical trial translation. But I ain't done yet. Today we'll dump on everyone else. Whatever Goldilocks may say, unrealistically high MAPI standards are less of a problem then the general lack of professional translation standards often employed in the clinical trial process. In most stateside trials, translation is notable for its absence. Those who don't understand English are generally excluded from studies. Unfortunate, but understandable too. Declarations and reports aside, investigators have to confront limits of time and money when...

Over the last decade and a half as a principal at CliniTrans, I have worked on foreign language translation with about 200 institutional review boards and other clinical trial organizations. The Declaration of Helsinki, the Belmont Report, the requirements of the FDA and similar regulatory bodies all establish a firm basis for the provision and execution of accurate and accessible communication for non-English speakers participating in clinical trials. The most widely recognized clinical trial translation methodology for patient-reported outcome instruments is perhaps the most rigorous quality assurance process used in the translation industry. In fact, it's so tough and expensive that no one uses...