Coffee & the Risk of Death From Heart Disease & Cancer

Last month, I reviewed research showing thatcause, during this decade-long public health study.
increased coffee consumption was associated with aThe coffee-associated reduction in the risk of death
decrease in inflammation and an increase in HDLfrom cardiovascular disease was even more powerful
cholesterol (the "good cholesterol"). However, as I(and also appeared to be "dose-dependent"), as the
noted in that column, this small study did not addresswomen who downed 3 or more cups of coffee per
any long-term health outcomes of frequent coffeeday experienced a whopping 55 percent decrease in
consumption (Coffee Improves HDL Cholesterolthe risk of death due to cardiovascular causes! Finally,
Levels). Now, a newly published prospective publicthere was an apparent modest decrease in the risk
health study, from Japan, suggests that regularof dying from colorectal cancer among the female
coffee consumption may, indeed, have long-termcoffee drinkers, but no other reduction in the risk of
health benefits (at least for half of the population...). (Idying from cancer was observed in association with
should also note that, as a disclaimer, I am not aregular coffee consumption among these women
coffee drinker, despite reviewing two coffee-relatedvolunteers.
health research studies in as many months!)Well, I have just shared with you the good news
The results of this large Japanese research studyregarding reduced death rates associated with regular
appear in the current issue of the Journal of Nutrition.coffee consumption from this large, prospective,
In this prospective epidemiological study, 18,287 menlong-term public health study; and many of you will
and 19,455 women (between the ages of 40 and 64notice that I have not yet mentioned the health
years) were prospectively included in the Miyagiimpact of coffee on men! This is because,
Cohort Study, which began in 1990. All of theseunfortunately, this study did not identify any
study volunteers were without any clinical history ofapparent beneficial health effects of regular coffee
cancer, heart disease, or stroke when they enteredconsumption in men.
into the Study. After an average of more than 10The reason, or reasons, for this gender-related
years of follow-up, 2,454 of the volunteers died fromdisparity is not clear, although it is well known that
various causes, including 426 cases of fatalthere are major differences in both the incidence of
cardiovascular disease and 724 fatal cases of cancer.cardiovascular disease between men and women,
These volunteers were categorized and analyzedand differences in the way that cardiovascular
according to their self-reported daily consumption ofdiseases (and heart disease, in particular) manifest
coffee: "never-drinkers," "occasional-drinkers," 1 to 2themselves in women versus men. It is, therefore,
cups per day, and 3 or more cups per day. Otherpossible, that cardiovascular disease factors that are
known risk factors for cardiovascular diseasemore unique to women are directly impacted upon
(including heart disease and stroke) and cancer wereby regular coffee consumption. (At least no adverse
also factored into the analysis of the risk of deatheffects of regular coffee consumption on male
associated with coffee consumption for eachmortality were observed in this large public health
volunteer.study!)
Among the women in this study, increasing levels ofSo, ladies, keep the favorable results of this clinical
daily coffee consumption were associated aresearch study in mind whenever you order that
decreasing risk of death, due to any cause. (Thisnext cuppa Joe!
"dose-dependent" relationship between daily coffeeTo learn more about the role of coffee, and other
consumption and risk of death strongly suggests asources of dietary tannins, as potential cancer
direct clinical relationship between increased coffeeprevention nutrients, look for the publication of my
consumption and a decreased risk of death.) Whennew landmark evidence-based book, "A Cancer
compared to the women who did not drink coffee atPrevention Guide for the Human Race," in the
all, the women who drank 3 or more cups of javasummer of this year.
per day were 25 percent less likely to die, from any